![]() ![]() However, this study has two major drawbacks. The reason for this increased mortality risk was uncertain. Ī recent study reported that of the 230 patients they followed up over 8 years, significantly more with COP-induced myocardial injury (n = 32/85) than without (n = 22/145) died. For example, epidemiologic studies by the USA’s Centers for Disease Control and Prevention, use International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) death certificate codes for cause of death but warn the reader that the “one code specific to CO (T58)” does not distinguish between motor-vehicle exhaust-related deaths and other CO-related deaths. Reports of COP-related deaths include only short-term mortality that is clearly related to acute CO toxicity. Failing to diagnose COP can have disastrous consequences. Particularly during cold weather, physicians should suspect COP in patients with acute coronary syndrome and arrhythmias. The most common symptoms are headache, dizziness, nausea/vomiting, confusion, fatigue, chest pain, shortness of breath, and loss of consciousness. Symptoms are required for diagnosis, but no single symptom of COP is sensitive or specific enough to warrant a definitive diagnosis of COP. Ī diagnosis of COP requires recent CO exposure, symptoms consistent with COP, and an elevated COHb level. ![]() COP is the second leading cause of unintentional poisoning deaths and, together with intentional exposures, annually contributes to approximately 2700 fatalities. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.Ĭarbon monoxide poisoning (COP) is common in the United States it accounts for an estimated 50,000 emergency department visits annually. The interpretation and conclusions contained herein do not represent those of National Health Insurance Administration, Ministry of Health and Welfare or National Health Research Institutes. It is based in part on data from the National Health Insurance Research Database provided by the National Health Insurance Administration, Ministry of Health and Welfare and managed by National Health Research Institutes (Registered number NHIRD-100-057). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: This study was supported by grant CMFHR10252 and CMFHR10334 from the Chi-Mei Medical Center. Received: MaAccepted: JPublished: August 28, 2014Ĭopyright: © 2014 Huang et al. ![]() PLoS ONE 9(8):Įditor: Gianluigi Forloni, “Mario Negri” Institute for Pharmacological Research, Italy (2014) Long-Term Prognosis of Patients with Carbon Monoxide Poisoning: A Nationwide Cohort Study. Citation: Huang C-C, Chung M-H, Weng S-F, Chien C-C, Lin S-J, Lin H-J, et al. ![]()
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